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The imbalance between the availability of lipids in the liver and their metabolism (e.g., catabolism and transport) contributes to hepatic steatosis, a reversible condition that occurs in both ALD and MASLD that can progress to advanced stages, such as alcoholic steatohepatitis and MASH that ultimately can culminate in HCC [114116]

Its well established that ROS generation is an essential modulator of inflammatory reactions in mammals

It plays a fundamental role in maintaining cellular health, primarily by serving as a potent antioxidant and participating in various enzymatic reactions throughout the body