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Brain 135, 36993711

Bidram E, Esmaeili Y, Amini A, Sartorius R, Tay FR, Shariati L, et al

Evidence in recent years is demonstrating that elevated levels of peripheral proinflammatory signals are observed during all phases of BD, and that patients with autoimmune diseases present an increased risk of BD diagnosis

A phase I safety study in healthy adults confirmed that subcutaneous MOTS-c injections at doses up to 10 mg produced no serious adverse events, with a pharmacokinetic profile supporting once-daily or every-other-day dosing [3]