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Toxicology 328 , 1220 (2015)

2.5 Immune dysfunction In UC, intestinal inflammation is driven by sustained dysregulation of both innate and adaptive immunity, which together propagate and amplify mucosal injury (Yue et al., 2024)

Each main group (healthy and tumorized) was divided into four subgroups for treatments with free curcumin (FC), non-targeted dendrimeric curcumin (DC), mitochondria-targeted dendrimer without curcumin (TD), mitochondria-targeted dendrimer with curcumin (TDC), and PBS as the control group

BSE resulted in a 0.2 mmol/L reduction in fasting blood glucose compared to placebo (95% confidence interval -0.44 to -0.01, p=0.04), which did not meet the predefined outcome of 0.3 mmol/L