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This has a big impact on many diseases, such as neurological diseases, age-related diseases, and neurodegenerative disorders like Parkinsons and Alzheimers (31)

Hsd3b1 mRNA levels were significantly higher in LCs treated with 10 g/L (0.03 IU/L) rhGH but Hsd3b1 mRNA levels of 50 g/L (0.15 IU/L) rhGH treated LC were significantly lower than those of controls

Gisondi P, Geat D, Conti A, Dapavo P, Piaserico S, De Simone C, Bianchi L, Costanzo A, Malagoli P, Malara G, Micali G, Naldi L, Offidani A, Patrizi A, Prignano F, Parodi A, Rongioletti F, Calzavara-Pinton P, Girolomoni G (2020c) TNF-alpha inhibitors biosimilars as first line systemic treatment for moderate-to-severe chronic plaque psoriasis