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Although low-affinity mAbs have low efficacy, high-affinity mAbs might demonstrate more adverse events due to binding to all EpCAM+ cells

Key institutional supporters of inclusion include the Alliance for Pharmacy Compounding, Empower Pharmacy, Hims & Hers Health, the American Institute for Compounded Therapeutics, and the Texas Pharmacy Association, all of which submitted comments arguing that restricting legal compounding does not eliminate demand but displaces it into unverifiable supply chains

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Adding to doctors worries are concerns about purity and dosing, because users typically buy from websites selling unregulated Chinese product some of which comes from plants that previously produced the deadly opioid fentanyl