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Mitochondrion-Permeable Antioxidants to Treat ROS-Burst-Mediated Acute Diseases

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Wild-type p53 promotes apoptosis through the transcriptional activation of proapoptotic genes such as Bax and PUMA [48]

Expression analysis of GPX4 mRNA in DLBCL To determine whether GPX4 is overexpressed at the protein level or at the mRNA level in DLBCL, we first evaluated the GPX4 protein expression level in 48 DLBCL cases by immunohistochemistry and, depending on the results, divided into two groups, GPX4-positive and GPX4-negative group, according to the criteria described above