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The NCI-MATCH subprogram (NCI-Molecular Analysis for Therapy Choice) is a large scale precision medicine clinical trial officially launched by the National Cancer Institute (NCI) in August 2015 (O'Dwyer et al., 2023)

GSH scavenges excess free radicals in the body by oxidizing the sulfhydryl group (-SH) of GSH to produce oxidized GSH (GSSG) through the catalysis of GSH-Px, which consumes H2O2 to produce water (13)

However, these results should be interpreted with caution due to high heterogeneity that was observed among the studies included in this meta-analysis