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The ROS are counteracted naturally by antioxidant defense systems, such as superoxide dismutase (SOD), which is considered an essential antioxidant marker present in almost all cells to provide the first line of defense against the toxic effects of ROS accumulation by converting them into less reactive hydrogen peroxide

Efek jangka panjang yang belum teruji , karena sebagian besar klaim manfaat tidak memiliki dasar ilmiah kuat Selain hal itu, diperkuat juga oleh WHO dan Ikatan Dokter Indonesia (IDI) menegaskan bahwa efektivitas glutathione sebagai pemutih kulit belum terbukti secara klinis , sehingga klaim manfaat kulit lebih putih tidak dapat dipertanggungjawabkan secara medis

Mechanism of Action Boosting Glutathione Production NAC serves as a precursor to cysteine, which is the rate-limiting substrate needed for glutathione synthesis

[Google Scholar] Yee S, Choi BH