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Our team with clinical studies on Alzheimers patients has shown that iron deposition in the hippocampus along with decrease in the levels of the antioxidant glutathione in the same area of the brain is one of the important factors of the disease, says Dr Pravat Mandal, senior scientist and former director-in-charge of the National Brain Research Centre The recent approval of three drugs to prevent cognitive decline in Alzheimers patients came as a ray of hope for many but could there be other factors at play

Quality assessment of the included studies The Systematic Review Centre for Laboratory Animal Experiments (SYRCLE) tool was used to determine the "risk of bias" in the included studies (Figure 2) []