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Discovering and developing new peptides is a rapidly developing area of science, particularly peptides derived from the mysterious part of the human genome referred to as junk DNA

The mitochondrial creatine kinase isoform (mtCK), in particular, forms a multienzyme complex with the adenine nucleotide translocator (ANT) and the voltage-dependent anion channel (VDAC), effectively coupling mitochondrial ATP synthesis to cytosolic ATP utilization [11]

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These data were in line with the hypothesis that neuromuscular junctions, which are the synapses between MNs and muscle fiber, could represent the starting site of MN dysfunction in ALS [269]