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Li L, Wang Z, Li Y, Ma F, Wang X, Yan H, et al

5 d, 24 h: Ctrl, n = 6 mice

Adv Exp Med Biol (2015) 803:191201

A phase 1 study of the DOT1L inhibitor, pinometostat (EPZ-5676), in adults with relapsed or refractory leukemia: safety, clinical activity, exposure and target inhibition Blood 126 , 2547 (2015)