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(1997) reported that PD patients who received long-term levodopa treatment had elevated plasma bilirubin levels, showing a protective effect, whereas in most studies, treatment of PD patients was not recorded, making it impossible to adjust for drug effects, thus leading to bias in cross-sectional comparisons (Songsomboon et al., 2020)

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187189,191,192 It also improved response rate, stable disease period, inflammation, quality of life, and survival rate, and reduced the burden of chemotherapeutic side effects among these patients