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In addition, we found that alloxan treatment significantly elevated the level of AST in serum and suppressed the enzyme activity level of TrxR in the liver

In mice, daily oral administration of a high dose of ergothioneine (70 mg/kg/d) for 28 d showed that while ergothioneine primarily accumulated in liver and whole blood, levels also increased in multiple tissues including kidney and brain (Reference Tang, Cheah and Yew38)

Different types of MN (hollow MN, swellable MN, porous MN, coated MN, and dissolvable MN) extract ISF through semi-invasive principles like vacuum drive, polymer expansion, capillary action, and specific recognition

Measurement of ROS generation using DCFDA staining ROS generation was examined in vitro on E9 cells and in vivo in zebrafish larvae using the DCFDA staining method, as described previously 52