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Nashimoto et al., 2020)

Biomaterials 32, 61646173

A 2016 study published in Nature Scientific Reports showed that GHK-Cu had no cytotoxicity to human keratinocytes at concentrations up to 5,800 micromolar over 72 hours and did not induce inflammatory biomarkers

This stability is attributed in part to the presence of proline residues, which help protect the peptide from enzymatic breakdown and support its potential as a research chemical in studies involving the gastrointestinal tract and other tissues