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J Diabetes its Complications

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Specifically, PDHC catalyzes the conversion of pyruvate to acetyl-CoA, and OGDC catalyzes the oxidation of -ketoglutarate (-KG) to succinyl-CoA

While traditional therapies have focused on lowering IOP to protect the optic nerve, this dual approach also aims to slow or prevent neurodegenerative processes, offering a more holistic solution to preserve vision