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Bentivegna A, Roversi G, Riva G, Paoletta L, Redaelli S, Miloso M, et al

In a June 2025 position document, the regulator noted the rise of unauthorized and counterfeit semaglutide products and stated that sterile compounding is a high-risk activity that should generally be reserved for exceptional circumstances, such as a patient-specific need that cannot be met by an approved drug or a true shortage

Furthermore, chronic hypoxia, particularly in high-altitude populations, has been associated with worse outcomes in patients with pre-existing cardiorespiratory conditions [41,46]