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Transient drug-tolerance and permanent drug-resistance rely on the trehalose-catalytic shift in Mycobacterium tuberculosis

( 2.1.2 Long term stress (chronic stress) Prolonged stress can lead to chronic inflammation, with continuous production of inflammatory cytokines ( 2.2 Immune activation and immunosuppression caused by CORT The behavioral changes induced by fluctuations in cyclic CORT levels exhibit a holistic nature