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Once inside the enterocytes, IF is degraded in the lysosomes and Cbl is released into the cytosol ( LMBRD1 and ABCD4 are lysosomal membrane exporters), where it is transported across the ileal receptor cell and released into the bloodstream, possibility by the multidrug resistance protein MRP1 (see Table 1

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DOI: 10.1530/EC-18-0514 Camacho EM, Huhtaniemi IT, ONeill TW, et al

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