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The Guidance expressly provides that it does not address products that are not tobacco products and that only [l]iquids that do not contain nicotine or other material or derived from tobacco, but that are intended or reasonably expected to be used with or for the human consumption of a tobacco product , may be components or parts and, therefore, subject to FDAs tobacco control authorities. (Emphasis added)

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Animal models The use of flavors increases the appeal and preference for e-cigarette use, especially among young people