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Francis Crick proposed genetic code words (codons) as part of his adaptor hypothesis, which Marshall Nirenberg and Heinrich Matthaei at the NIH demonstrated with brilliant experiments in 1960 and 1961

Then we turn to a discussion of clinical and pre-clinical findings of redox impairment that induce brain pathology in schizophrenia, through mechanisms that likely involve aberrant inflammatory responses, mitochondrial dysfunction, oligodendrocyte abnormalities, epigenetic changes, hypoactive N -methyl-D-aspartate (NMDA) glutamate receptors and the impairment of fast-spiking gamma-aminobutyric acid (GABA) interneurons ( see Figure 1)