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Conclusion Mice deficient in both formaldehyde-metabolizing enzymes ADH5 and ALDH2 were found to develop partial synthetic lethality and mortality shortly after birth

The patients blood pressure declines within 30 to 60 minutes after an oral dose, the maximum decrease occurring within 2 to 4 hours

By comparing the survival rates of the parental strain and deletional strain under the stress of the H 2 O 2 , the results showed that the survival rates of the parental strain and the mutant were comparable at 10 mM sub-lethal concentrations (Figure 2A)