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Phase II Conjugation Reactions Phase II metabolism involves the conjugation of a bioactive drug or its phase I metabolites with large polar molecules to enhance solubility and elimination

With the help of the enzymes hexokinase, phosphofructokinase, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) and pyruvate kinase, glycolysis rapidly converts a single molecule of glucose into two molecules of pyruvate with a net gain of two ATP molecules and two molecules of NADH

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