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Microglia recognize synOs through pattern recognition receptors such as Tolllike receptor (TLR)2, triggering activation of the NLRP3 inflammasome and a proinflammatory cascade [161]

When tumors were increased to 100 mm 3 in volume, 100 L of DOX, or DOX/LAAM GSH-CQDs at a dose equivalent to 5 mg kg 1 DOX was injected into the mice veins ( n = 3)

After adding into the ELISA wells, incubate for 15min at 37C in dark.) Due to different assay environments and operations, assay data below and standard curve are provided for reference