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In a mouse model of breast cancer, the nanoparticles significantly reduced lung metastasis combined with inhibition of tumor growth and metastasis, which enhanced the anti-cancer effect

2.4.1 Mechanism of cycle formation: ferroptosis triggers inflammation, and inflammation exacerbates ferroptosis The lysis of ferroptotic cells releases DAMPs, such as high-mobility group box 1 (HMGB1), ATP, and mitochondrial DNA, which activate the NOD-LRR-purine domain protein 3(NLRP3) inflammasome in macrophages, promoting the maturation and release of IL-1 and IL-18 (50)

Pinch a layer of skin in the front thigh area with your thumb and index finger to inject the shot

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