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Clinically, PCOS patients exhibit reduced gut microbial -diversity, an elevated Bacteroidetes-to-Firmicutes ratio, and decreased abundance of beneficial bacteria such as Akkermansia muciniphila

However, our in silico modeling, developed to predict the conformational landscape of these molecules, indicates that only a minor population of the analogs adopt conformations of the warhead near Cys13 to achieve covalent interaction

An endogenous retrovirus is a section of our human DNA that is likely the integration of a virus or provirus incorporated into the genome millions of years ago

doi:10.3389/fimmu.2023.1253121 Jurek JM, Castro-Marrero J