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Indeed, it has been shown that supplementation of sows with 50 mg l-carnitine/kg diet increases free and total carnitine concentrations in liver, skeletal muscle and heart of the fetus at days 55 and 70 of gestation, and moreover increases the activity of carnitine palmitoyltranferase-I in the liver ( Reference Brown, Goodband and Tokach 47 , Reference Xi, Brown and Woodworth 48 )

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Nat Rev Immunol 8:923934 Ishii KJ, Koyama S, Nakagawa A, Coban C, Akira S (2008) Host innate immune receptors and beyond: making sense of microbial infections