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According to research, treating tumor cells with these nanoparticles modulates the expression of critical apoptotic genes such as the tumor suppressor gene p53, bax, caspase-3, and Bcl-2 [252]

South America and the Middle East have the highest prevalence, followed by Asia, while Africa has the lowest (12)

129 Among the various inflammatory cytokines produced by innate immune cells in response to SARS-CoV-2 infection, it has been identified that the co-production of TNF and IFN- uniquely triggers PANoptosis