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doi: 10.3390/agronomy12020276 Summary Keywords climate change, cold stress, crop improvement, low temperature, signaling Citation Roychowdhury R, Das SP, Sarkar P, Khan Z, Kumar A, Sarker U and Sajeevan RS (2025) Physiological, biochemical and molecular signaling basis of cold stress tolerance in plants

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Furthermore, nicotinamide adenine dinucleotide phosphate (NADPH), derived from niacin, is crucial in antioxidant defense mechanisms, by aiding in the regeneration of other antioxidants, such as glutathione (13)

Curcumin-inducible HIF-1 degradation has been shown to impede the process of invasive metastasis in colorectal cancer cells by impeding glutamine catabolism through the inhibition of GLS1 and the suppression of EMT [66]