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L-carnitine enhances fatty acid entry into the mitochondria, mitigating their toxic effects in the cytosol, and decreasing the inhibitory effect of acetyl-coenzyme A on the pyruvate dehydrogenase complex caused by intramitochondrial acetate.14 Studies that evaluate L-carnitine supplementation in critically ill patients suggest that it reduces inflammatory biomarkers compared to placebo.15,16 In addition, serum levels of carnitine and its esters in patients with sepsis and septic shock are strong predictors of patient mortality

Ann Med Health Sci Res

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