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ROS can interfere with the functions of macromolecules such as protein oxidation, disintegration of plasma membranes through lipid peroxidation as well as alterations of permeability, integrity and oxidation of RNA and DNA

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Even so, these latest revelations are sure to increase the pressure on British Athletics, who have stood loyally by the legendary endurance coach ever since the BBCs Panorama suggested that he may have committed anti-doping violations two years ago

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