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Conclusions The multifunctional nanomedicine PDA@Pt exhibits exceptional efficacy in UA reduction and anti-inflammatory effects, presenting a promising potential therapeutic strategy for the management of acute gout

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This is in contrast to the absence of the HLA-B*57:01 allele, which has an NPV of 100% for abacavir hypersensitivity (a reaction distinct from SJS/TEN, though illustrative as an example)

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