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The inflammatory process, though necessary for healing, can lead to swelling, redness, and mild sensitivity

Chemicals: Solvents, inorganic salts, and organic reagents were purchased from commercial sources such as Sigma and Fisher and used without further purification unless otherwise noted

Prolonged and frequent exposure to polluted air and inhalation of ambient particles may impair the antioxidants ability to neutralise reactive oxidative species generated by heavy metals and other toxic substances

Tadashi Isa (Kyoto University Graduate School of Medicine, Department of Neuroscience) for their invaluable supports of the research