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Etesian: a phase 2B study of the efficacy, safety and tolerability of AZD8233, a PCSK9-targeted antisense oligonucleotide, in patients with dyslipidemia [abstract]

This progressive neurodegenerative disorder is characterized by distinct pathological features, including the accumulation of iron in the substantia nigra pars compacta (SNc) and the aggregation of -syn within Lewy bodies, ultimately leading to the degeneration of dopaminergic neurons [2, 3]

[14] NAD + and NADP + bind within the active site within four regions with similar properties amongst IDH enzymes

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