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doi: 10.1016/j.freeradbiomed.2007.05.022 McElhaney JE, Beattie BL, Devine R, Grynoch R, Toth EL, Bleackley RC: Age-related decline in interleukin 2 production in response to influenza vaccine

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The current GHK-Cu FDA approval status is mainly influenced by high drug development costs, limited clinical data, formulation stability challenges, and its established role as a GHK-Cu cosmetic ingredient