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Funding This work is supported by the National Natural Science Foundation of China (Grant No

We began exploring the efficacy of senolytics in tauopathy mouse models to determine the impact of senescent cells on brain structure and function relevant to AD neuropathology (35)

Although naproxen is considered to be a safe non-steroidal anti-inflammatory drug, it has a number of side-effects including gastrointestinal toxicity, nephrotoxicity, jaundice and hepatotoxicity