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2025a;12:e06150

In a different study, the impact of methotrexate was evaluated in a Swiss mouse skin tumor model methylcholanthrene (MCA)

CGI-C of much improved or very much improved was achieved in 26% of patients on placebo, 28% receiving 12 mg/day, 49% receiving 24 mg/day, and 44% on 36 mg/day