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Materials and methods Animals and ethics approval Twenty-four rats ( Rattus norvegicus , SpragueDawley, male, 180 g 10 g) were obtained from the Atatrk University Medical Experimental Application and Research Center (Erzurum, Turkey)

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Availability of data and materials Data and materials related to the present work will be made available on request by the corresponding author References Azab AE, Albasha MO, Elsayed AS

Following distribution to many tissues and organs in the body including the lungs, heart, kidneys, liver, muscles, and neural tissue, As is metabolized to monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA) in which the latter is the predominant form in the urinary excretion of As (Del Razo et al., 1997