A second hydrogen peroxide molecule acts as a reducing agent to regenerate the resting state enzyme, producing a molecule of oxygen and water.36 Hydrogen peroxide though at low amounts tends to regulate some physiological processes such as signaling in cell proliferation, cell death, carbohydrate metabolism, mitochondrial function, and platelet activation and maintenance of normal thiol redox-balance,37 however, at high concentrations it has been reported to be very deleterious to cells.38 Hence, the ability of CAT to effectively limit H2O2 concentration in cells underlines its importance in the aforementioned physiological processes as well as being a first line antioxidant defense enzyme
A deficiency in CoQ10 has been associated with an increased risk of various conditions, including diabetes, fibromyalgia, neurodegenerative diseases, and heart failure
According to above criteria we chose vitamin D, selenium, vitamin B 12 , vitamin C, zinc and vitamin A (2629)
Additionally, its muscle-relaxing effects increase the likelihood of obstructive sleep apnea, leading to irregular breathing, snoring, and further impaired sleep quality (Simou, Britton & Leonardi-Bee, 2018)
