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Thus, selective c-Met inhibitors may be a better choice for treatment in patients and more studies are needed to identify the reason for phase II clinical trial failure and the feasibility of using c-Met targeting therapies

In addition to education on proper treatment administration, the participants of the study also received dietary and physical activity counseling aimed towards achieving 150 minutes of physical activity per week and a 500 calorie deficit per day

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The hMPV F polypeptide or nucleic acid molecule of any one of claims 8-14, wherein said prefusion F polypeptide further comprises an Fo cleavage site mutation comprising amino acid substitutions Q100R and S101 R, replacing glutamine at amino acid position 100 of SEQ ID NO: 1 with arginine, and replacing serine at amino acid position 101 of SEQ ID NO: 1 with arginine