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The ability of benfotiamine to inhibit three major pathways (the hexosamine pathway, the AGE formation pathway, and the diacylglycerol (DAG)-PKC pathway) simultaneously might be clinically useful in preventing the development and progression of diabetic complications

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[DOI] [PMC free article] [PubMed] [Google Scholar] 88.Halfdanarion T.R., Kumar N., Hogan W.J., Murray J.A