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The Root Cause Most People Miss: Your Guts Cleaning System Understanding the Migrating Motor Complex Your gut has a built-in cleaning mechanism that is called the migrating motor complex

The core issue is that targeting metabolic pathways (such as glycolysis and OXPHOS) is also crucial for the physiological functions of normal cells, making systemic metabolic inhibitors a double-edged sword and prone to causing widespread off-target toxicity (135)

Inflammation and gut microbiota play crucial roles in both psychological distress and liver disease initiation and progression, while the sickness behavior theory explains that peripheral inflammation can lead to behaviors like fatigue, lethargy, impaired concentration, and social withdrawal

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