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Powderly JD, Klempner SJ, Naing A, Bendell J, Garrido-Laguna I, Catenacci DVT, et al

Differential effect of nitric oxide on glutathione metabolism and mitochondrial function in astrocytes and neurones: implications for neuroprotection/neurodegeneration

The modulatory mechanisms involved in NF-kB regulation by phytochemicals result in reduction of TNF-, IL-1, IL-6, IFN-, and COX-2 levels and augmented occludin, claudin-1, zonula occludens-1, and IL-10 expression

However, also in context of diseases, cell metabolism alterations have been observed and over the past years, multiple studies focused on understanding cell metabolism changes in various pathophysiological conditions, including inflammation and atherosclerosis - with the aim to develop new therapeutic strategies