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Airway DCs: Immunological Sensors of Environmental Air Quality The lung is constantly exposed to airborne antigens, hence a thorough surveillance of this large organ by the immune system is of vital importance

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In addition, avoiding direct comparison between the harms of traditional cigarettes and ENDS is recommended due to existing uncertainties, in particular those related to the high prevalence of dual or multiple product use, the variability of types/generations of ENDS and in their levels of nicotine content, and to a lack of rigorous and standardised comparative studies