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Pal et al., 2023)

Permeability study In addition to TEER measurements, Lucifer yellow (100 M, Sigma-Aldrich) dissolved in phenol red-free DMEM (Biochrom) was added to the apical compartment of the Snapwells to determine the integrity of the cellular layer

Discussion Epothilone derivatives are one of the most potent antimitotic drugs that halt the cellular multiplication, stopping the cell cycle at G2/M phase, with an ultimate apoptosis/cell death [35]

The FDA also requires that the NDA (New Drug Application) have a section demonstrating that potential consumers can understand the information included in the label and can use the medication appropriately without a doctors instructions (this is referred to as label comprehension)