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After intravenous injection of PCB micelles for 24 h, the temperature of the tumor site in HepG2 tumor-bearing mice rapidly increased from 37C to 67C within 5 min under 808 nm laser irradiation

These findings were corroborated in the work presented by Song et al., who showed that ovarian cancer could induce endoplasmic reticulum stress in cytotoxic T cells, which depleted glutamine transporters in these cells and subsequently led to T-cell dysfunction [152]