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The mechanism in one sentence: hollow gold-plated microneedles at fixed 0.5mm depth create temporary channels through the stratum corneum, the upper epidermis, and into the papillary dermis where fibroblasts live

The incorporation of reduced graphene oxide (rGO) and R-Gel facilitated the in situ reduction of Cu 2+ to Cu + and enhanced system stability under marine conditions (Li H

MLO Targeting: The optimized sensor (miniGrx1-roGFP2) with a 20-amino-acid linker was targeted to specific MLOs (nucleoli, stress granules, p-bodies, nuclear paraspeckles, and Cajal bodies) and their surrounding environments (cytosol and nucleoplasm) using established localization signals

reuteri and Bifidobacterium can be tested in the future to verify its efficacy against NEC