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it cannot establish superiority, because differences in population, comparator, endpoint, dose, and trial length confound any direct read

Journal of Investigative Dermatology , 117(5), 1125-1135

Week one through two: Initial increase in breakouts or texture

Cagrilintide vs tirzepatide Tirzepatide is a dual GIP/GLP-1 agonist that produces the highest monotherapy weight loss results currently available, approximately 22.5% at the maximum dose