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It acts on several levers: Thermogenesis: natural heat production by the body to burn more calories Lipolysis: breakdown of fats stored in adipocytes Appetite regulation: some active ingredients have a natural appetite suppressant effect that helps limit cravings Energy and vitality: caffeine or guarana-based formulas increase alertness and energy expenditure Most effective fat burners contain plant extracts such as green tea, citrus aurantium, guarana, spirulina or L-carnitine, known for their role in energy metabolism

Subsequently, the intermediate product 5caC is removed by thymine DNA glycosylase (TDG) and repaired through the base excision repair (BER) pathway, thereby achieving active demethylation and maintaining dynamic balance [9]