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Sienaert P, De Hert M, Houben M, Bouckaert F, Wyckaert S, Hagon B, Hagon A, Peuskens J

549 Phase I studies showed that a single subcutaneous dose of zilebesiran of 200 mg or more considerably decreased serum AGT levels and 24 h ambulatory blood pressure for up to 24 weeks, with only mild injection site reactions observed