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We propose a mechanism that underlies an antitumor response of CD8 + T cells by modulating GSH metabolism and A2AR signaling (Supplemental Figure 11)

Interestingly, the joint diameters in the mice immunized with VLP-CspZ-Y207A/Y211A were at least threefold less than VLP-immunized mice at 7 and 14 days post infection, but were no different than uninfected mice (Figure 4)